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1999). "Biochemical studies of human white blood cells show that high-dose therapy with omega-3 fatty acids leads to the incorporation of these polyunsaturated compounds includes bibliographical references and indexes. into the membrane phospholipids crucial for cell signaling," said Stoll and colleagues (1999). "Increased concentrations of omega-3 fatty acids in membrane phospholipids appear includes bibliographical references and indexes. to suppress phosphatidylinositol-associated signal transduction pathways [Medini et al.,1990; Sperling et al., 1993]. "The precise mechanism of this effect remains unclear. However, the incorporation of the polyunsaturated omega-3 includes bibliographical references and indexes. fatty acids into the lipid bilayer of the cell membrane alters the physical and chemical properties of the membrane [Barton and Gunstone, 1975], possibly producing a local environment in which the membrane phospholipids are more resistant to hydrolysis by phospholipases.
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