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To a very limited extent, omega-3 fatty acids from vegetable epilepsy sources, such as flaxseed oil, can convert to EPA. At least four studies have reported a reduced blood level of omega-3 fatty acids in people with depression.18 19 epilepsy 20 21 People with rheumatoid arthritis have been found to have decreased levels of omega-3 fatty acids, such as are found in fish oil, in their joint fluid and blood.22 How much is usually taken? Presumably, healthy people who frequently eat fatty fish (several times per week) have no epilepsy need to supplement with fish oil. How much EPA and DHA, if any, should be supplemented by healthy people who do not eat much fatty fish, remains unclear. Most researchers studying the effects of EPA and DHA in humans who have a variety of health conditions have given those people at least 3 grams of the total of EPA plus DHA—an amount that may require 10 grams of fish oil, because most fish oil contains only 18% EPA and 12% DHA. The health benefits for people with Crohn’s disease have been reported with a special, enteric-coated preparation of purified EPA/DHA manufactured from fish oil.
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