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MacLean et al (J. Am. Med. docosahexaenoic acid Assoc. 2006 295:403):1) Studies show that tissue levels of arachadonic acid and eicosopentaenoic acid (EPA)-derived eicosanoids influence many physiological processes, including calcium transport across cell membranes, angiogenesis, apoptosis, cell proliferation, and immune cell function.[1-4] These processes are docosahexaenoic acid integral to the immune system and hence the pathogenesis of autoimmune diseases such as arthritis, systemic lupus erythematosus, and asthma, as well as cancer. Epidemiological studies have suggested that groups of people who consume diets high in omega-3 fatty acids may experience a docosahexaenoic acid lower prevalence of some types of cancer,[5] and many small trials have attempted to assess the effects of omega-3 fatty acids on cancer treatment by adding omega-3 fatty acid to the diet either as omega-3 fatty acid rich foods or as dietary supplements. In addition, dietary omega-3 fatty acids have been found to modulate mammary tumor formation and proliferation in rodents.2(
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