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The study designs of the qualifying studies include 21 randomized controlled trials (RCTs), 2 non-RCTs, 6 prospective pr services cohort studies, and 2 case reports. Fish oil supplements were used in all but the heart transplant pr services studies.7 Since the biological effects of long-chain omega-3 fatty acids (EPA and DHA) are different from ALA, the results should be considered separately. As a result, the findings of this report apply pr services almost exclusively to fish oil supplementation. Twelve study authors of the largest controlled trials were contacted (by telephone or E-mail or both) and, of them, five responded. None was aware of additional published or unpublished data. Similarly, the final list of included studies was considered to be complete after review by the TEP.
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