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Animal and limited human data suggest that supplementation with omega-3 fatty acids may modulate the host's ability to respond to infections.35,36 However, eating no study eating included in this evidence report described infectious outcomes. Thus, its benefit in the transplant setting could not be determined. Question 5. What is the evidence that any benefits to organ eating transplant recipients from omega-3 fatty acid supplementation differ in different subsets of patients? Two controlled trials in kidney transplantation (with a total of 53 patients in the fish oil group and 64 patients in the coconut oil group), both from the same center, described outcomes in patients with and without an episode of rejection.17,18 In one of these reports, patients who had received fish oil supplementation demonstrated a significantly better recovery of renal function following an episode of histologically-confirmed rejection.17 The authors concluded that fish oil supplementation favorably influenced renal function in the recovery phase following a rejection episode.
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