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In vivo studies have shown that EFA consumption reduces the production of these pro-inflammatory compounds, including cytokines IL-1 and tumor necrosis factor (TNF). Early research concentrated on rheumatoid rather than long term care osteo-arthritis as inflammation is the primary long term care symptom. There is now an accumulation of evidence to show that the long chain Omega-3 fatty acids can indeed reduce joint pain and stiffness and allow a reduction in dosage of the aspirin-like non-steroidal anti-inflammatory drugs (NSAIDs) that can damage the stomach lining and destroy connective tissue. An overall survey of 10 long term care double-blind, placebo-controlled, randomized trials confirmed that Omega-3 fatty acids taken for three months was indeed associated with a reduction in joint tenderness and morning stiffness. Osteoporosis According to scientific studies, Omega fatty acids have now been shown to increase calcium absorption from the intestines, in part by enhancing the effects of vitamin D, to reduce urinary excretion of calcium, to increase calcium deposition in bone and improve bone strength and to enhance the synthesis of bone collagen.
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