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• The increased omega-6/omega-3 ratio in Western diets most likely contributes to an increased incidence of cardiovascular disease and inflammatory disorders. • Patients with autoimmune diseases, such as rheumatoid arthritis, inflammatory bowel trans disease and asthma, usually respond to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation by decreasing the elevated levels trans of cytokines. trans Introduction TOP ABSTRACT Introduction Omega-6 and Omega-3 Fatty... Omega-3 Fatty Acids, Interleukin... Other Inflammatory Markers,... Fatty Acids, Cytokines, and... Rheumatoid Arthritis Inflammatory Bowel Disease Asthma Psoriasis Conclusions REFERENCES The first evidence of the important role of dietary intake of omega-3 polyunsaturated fatty acids (PUFAs) in inflammation was derived from epidemiological observations of the low incidence of autoimmune and inflammatory disorders, such as psoriasis, asthma and type-1 diabetes, as well as the complete absence of multiple sclerosis, in a population of Greenland Eskimos compared with gender- and age-matched groups living in Denmark [1].
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