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Dietary fish oils, rich in omega-3 PUFA, are rapidly incorporated into the membrane phospholipids of circulating human (monocyte) cells, suggesting that they are likely to have an effect on several aspects of ipo cell function. Moderate dietary supplementation with omega-3 PUFA significantly increases their level in monocytes within two weeks [36]. The levels of EPA reached a maximum accumulation after six weeks supplementation and DHA reached a ipo peak at 18 weeks [37]. EPA returned rapidly ipo to pretreatment levels in monocytes (although plasma levels remained significantly elevated from baseline after 24 weeks of washout) whereas DHA levels declined more slowly [37]. Omega-3 Fatty Acids, Interleukin-1 (IL-1) and Tumor Necrosis Factor (TNF) TOP ABSTRACT Introduction Omega-6 and Omega-3 Fatty... Omega-3 Fatty Acids, Interleukin... Other Inflammatory Markers,... Fatty Acids, Cytokines, and... Rheumatoid Arthritis Inflammatory Bowel Disease Asthma Psoriasis Conclusions REFERENCES The interactions between immune and inflammatory cells are mediated in large part by proteins, termed interleukins (IL), that are able to promote cell growth, differentiation and functional activation.
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