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Nausea, heartburn, or loose stools occasionally occur. Taking the capsules with meals may help. There's some concern that fish oil at higher doses (e.g., more than 3 grams daily) might blunt the immune response. That could be a problem for elderly individuals and those with suppressed immune function related to medications or diseases such as news and media HIV infection. Doses greater than 3 grams daily can thin the blood. Combining fish oil supplements with other blood-thinning drugs or supplements merits caution due to the potential risk of excessive bleeding. Such drugs include aspirin, news and media NSAIDs (e.g., news and media ibuprofen, naproxen), clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), and warfarin (Coumadin). Supplements include angelica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng, red clover, turmeric, willow, flaxseed oil, phosphatidylserine, policosanol, and high-dose vitamin E.
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