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However, the single study of a plant (rapeseed and linseed) oil found a non-significant but large net increase in Tg. Limited data suggest that the effect is not related to sex, age, baseline Tg level, weight, background diet, or lipid 1992 treatment. The effect of duration of intervention or exposure is unclear and there 1992 were no data regarding sustainment of effect. The effect of omega-3 fatty acids on other serum lipids was weaker. The 23 analyzed studies of total cholesterol and the 19 studies of HDL found heterogeneous results, but mostly found small, non-significant net increases in levels of both 1992 lipids. The 15 analyzed trials of LDL fairly uniformly found small net increases in LDL level. The effect of plant oils on these lipoproteins was possibly weaker, but was similar to the effect of marine oils. No differences in effect were seen by population across studies and in one study that performed a sub-analysis of diabetic subjects.
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