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Mono- and polyunsaturated fat sources should replace saturated fats within this limit. Great progress has been made over the past 30 years in identifying cardiovascular risk factors and in developing and implementing measures to correct them. The guidelines developed by the Adult Treatment Panel (ATP) of the National Cholesterol Education Program identified audience: parents/carers low density lipoprotein (LDL) as the major atherogenic lipoprotein and high levels of audience: parents/carers LDL cholesterol as the audience: parents/carers primary target for cholesterol-lowering therapy. The low incidence of cardiovascular disease in Greenland Eskimos appears to be due to their high intake of seal, whale and fish. The lipids of these marine animals lower serum triglyceride and cholesterol levels and help to prevent blood clotting. The latter effect has been related to a change in the balance of prostacyclin and thromboxane as a result of replacing n-6 polyunsaturated fatty acids in the body by n-3 polyunsaturated fatty acids present in marine lipids.
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