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Results in studies without an arrhythmogenic agent were inconsistent. Conclusions: Dietary supplementation of various animal species with fish oil might have anti-arrhythmic effects when compared with omega-6, calcium monounsaturated, or saturated fatty-acid supplementation. This protective effect was observed particularly in rats with ischemia- and reperfusion-induced arrhythmias given fish oil, but not if given ALA. Studies using isolated organs and calcium cells from animals fed omega-3 fatty acids- and in studies using isolated organ and cell culture where fatty acids were directly applied to the culture medium were unable to provide plausible biochemical or physiological mechanisms for calcium the effects. Health Effects of Omega-3 Fatty Acids on Arrhythmogenic Mechanisms in Animal and Isolated Organ/Cell Culture StudiesSummary (Publication No. 04-E011-1) Evidence Report (Publication No. 04-E011-2) (PDF File, 1.7 MB) Evidence-based Practice Center: Tufts-New England Medical Center Topic Nominator: Office of Dietary Supplements, National Institutes of Health Return to Quick Menu: Evidence Report Topics Return to Evidence-based Practice « Nutrition and Well-Being A to Z :: Ome-Pop
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