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| soy, better health, fat, caregiver of elderly, diabetes, 24 7 fat girls , probiotic, plump woman , askthe dietitian, vitamin e, carotenoid, politics in education, investor, hispanic newswire, children, flax seeds, transparency, lipid management, plump naked , colleges grad schools, | The remaining studies cannot resolve the divergent primary prevention results described by this study, even though each of the former failed to demonstrate a statistically significant association between exposure and outcome.14,15,17-19 Foremost among reasons is the use of research designs that constitute less than ideal strategies to investigate this question. These studies also varied alzheimer's disease in their definitions of the alzheimer's disease exposure, clinical outcome and/or confounders, which together make alzheimer's disease it impossible to draw a definitive conclusion regarding the potential of the intake of omega-3 fatty acids to prevent the onset of either early or late ARMD. The nature of the RCT design and the "cocktail-like" exposure employed by Scorolli et al. |
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| If it can be assumed that the study designs likely best suited to address this question should be both controlled and prospective, none of the included studies would qualify. The only prospective study included a large sample flax seeds and appropriately conducted multivariate analysis, and controlled for key confounders.14 These investigators observed that the consumption of canned tuna fish or more than four fish servings per week each flax seeds played a protective role against ARMD. However, their results also indicated that several types of oily fish well known to have high concentrations of DHA and EPA (i.e., sardines, mackerel) failed to show flax seeds a similar, protective effect. These discordant observations will require an explanation before anything conclusive can be asserted based on this study alone. Moreover, their study design did not a priori employ a separate, unexposed cohort as a control. |
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