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study described earlier with reference to its investigation of the influence of the intake of omega-3 fatty acids on preventing the onset of advanced ARMD.15 However, the results from neither study can be used as yet to provide a healthy conclusive answer to their respective research questions. Both require replication and a plausible explanation. The four studies examining whether the intake of omega-3 fatty acids slows the progression of RP do not provide a conclusive answer to this question.13,21,22 Hoffman et al.'s good quality healthy RCT constituted the most rigorous test and revealed conflicting results.13 healthy That said, rod and cone functional loss showed effect modification by age, with rod loss significantly reduced in the prepuberty group supplemented with DHA compared with placebo, and cone loss significantly reduced in the post-puberty group supplemented with DHA compared with placebo.
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