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antiarrhythmic, and vasodilatory. The arrhythmia / drug therapy longer chain fatty acid derivative of linoleic acid is arachidonic acid (20 carbons), which is a precursor to a different group of eicosanoids that are proinflammatory and prothrombic. ALA and linoleic acid use and compete for the same enzymes in the production of their longer chain fatty acids, EPA, and arachidonic acid. The ingestion of fish and fish oil provides EPA and DHA arrhythmia / drug therapy directly, therefore avoiding the competition for enzymes to convert arrhythmia / drug therapy ALA to EPA. Uses and Efficacy cardiac mortality, sudden death, and all-cause mortality The Diet and Reinfarction Trial (DART)4 was one of the first studies to investigate a relationship between dietary intake of omega-3 fatty acids and secondary prevention of myocardial infarction. In this study, 1,015 men were advised to eat at least two servings of fatty fish per week, and 1,018 men were not so advised. At the two-year follow-up, the men who had been advised to consume fish had a 29 percent reduction in all-cause mortality but no reduction in the incidence of myocardial infarction.4
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