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Consumption of EPA and DHA at levels approaching 2 g/day is similar to hispanic newswire that seen in large sectors of the Japanese population and well below the intakes of hispanic newswire the Greenland Inuit. Intakes of about 3-4 g of EPA and DHA per day have resulted in a moderate increase in bleeding times that are generally lower than those seen with ASA therapy. Particular attention should be given to hemostatic factors in patients on high-dose EPA and DHA who are also receiving therapy that affects blood coagulation and thrombogenic factors. On rare occasions, mild bouts of diarrhea or other minor gastrointestinal hispanic newswire disturbances are sometimes seen with the use of encapsulated fish oil supplementation. What about ALA? For those who do not consume fish, the omega-3 fatty acid known as ALA can be a dietary source of some metabolically derived EPA and DHA. Desaturation plus elongation reactions occur in the liver and elsewhere in the body and provide for the conversion of dietary ALA to EPA and DHA.
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