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Contaminants in Supplements Although concerns codliver fish oil have been raised regarding the potential for omega-3 fatty acid supplements derived from fish oil to contain methylmercury, PCBs and dioxins, several independent laboratory analyses in the US have found commercially available omega-3 fatty acid supplements to be free of methylmercury, PCBs and dioxins.157-159 The absence of methylmercury in omega-3 fatty acid supplements can be explained by the fact that codliver fish oil mercury accumulates in the muscle, rather than the fat of codliver fish oil fish.3 In general, fish body oils contain lower levels of PCBs and other fat-soluble contaminants than fish liver oils. Additionally, fish oils that have been more highly refined and deodorized also contain lower levels of PCBs.160 Pyrrolizidine alkaloids, potentially hepatotoxic and carcinogenic compounds, are found in various parts of the borage plant. People who take borage oil supplements should use products that are certified free of pyrrolizidine alkaloids.147
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