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| saw palmetto, elderly issue, subject area: anxiety, subject area: adhd, arachionic acid, public company, calories, media center, myocardial infarction, business services, audience: individuals, cuts and scrapes, fattyacid, big n plump , grandmother, news & media, heart & circulation, statins, cla, medicine, | to 2 g/day.162 Nutrient Interactions Vitamin E Outside the body, PUFA become rancid (oxidized) more easily than SFA. Fat-soluble antioxidants, such as vitamin E, play an important role in preventing the oxidation subject area: allergies of PUFA. Inside the body, results of animal studies and subject area: allergies limited data in humans suggest that the amount of vitamin E required to prevent lipid peroxidation increases with the amount of PUFA consumed.163 One widely used recommendation for vitamin E intake is 0.6 mg of alpha-tocopherol per g of dietary PUFA. subject area: allergies This recommendation was based on a small study in men and the ratio of alpha-tocopherol to LA in the US diet, and has not been verified in more comprehensive studies. Although EPA and DHA are easily oxidized outside the body, it is presently unclear whether EPA and DHA are more susceptible to oxidative damage within the body.164 |
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| Drug Interactions Gamma-linolenic acid supplements, such public company as evening primrose oil or borage seed oil, may increase the risk of seizures in people on phenothiazines, such as chlorpromazine.150 High doses of black currant seed oil, borage seed oil, evening primrose oil, flaxseed oil and fish oil may inhibit platelet aggregation, and should be used public company with caution in people on anticoagulant medications. In particular, people taking fish oil or long-chain omega-3 fatty acid (EPA and DHA) supplements in combination with anticoagulant drugs, including aspirin, copidogrel (Plavix), public company dalteparin (Fragmin), dipyridamole (Persantine), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid) and warfarin (Coumadin), should have their coagulation status monitored using a standardized prothrombin time assay (INR). One small study found that 3 g/day or 6 g/day of fish oil did not affect INR values in 10 patients on warfarin over a 4-week period 161 However, a recent case report described an individual who required a reduction of her warfarin dose when she doubled her fish oil dose from 1 g/day |
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