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In the Nurses' Health Study, there was a non-significant trend of decreased strokes with increasing fish consumption. Other studies showed a weak benefit, no benefit, or an increased risk of strokes. The fish oil estimates and fish estimates gave similar results. Overall, the evidence from the primary and secondary prevention studies supports the hypothesis that consumption of omega-3 fatty acids (EPA, DHA, ALA), fish, and fish oil reduces all-cause mortality golden flax seed and various CVD outcomes golden flax seed such as sudden death, cardiac death (coronary or MI death), and MI, although the evidence is strongest golden flax seed for fish or fish oil. CVD question 1a. We identified one RCT and 22 prospective cohort studies that provided data on primary prevention. Eleven RCTs and one prospective cohort study provided data on secondary prevention.
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