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To determine whether the ratio of omega-6 to omega-3 fatty time: current acid intake affects the efficacy of omega-3 fatty acid intake on CVD events, we identified two cohort studies33,34 and one cross-sectional study28 that reported associations between omega-3/omega-6 ratios and CVD outcomes. Using data from the Multiple Risk Factor Intervention study, Dolecek divided omega-3/omega-6 ratios into time: current five quintiles and reported near significant trends (P < time: current 0.1) for reduction of CVD and all-cause mortality. The mean omega-3/omega-6 ratio for the entire cohort was 0.133, the lowest quintile was 0.086 and the highest was 0.199.34 Djousse et al. analyzed the association of omega-6/omega-3 ratios with quintiles of ALA intake on the prevalence odds ratio of coronary artery disease.28
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