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Fatty acids comprise the hydrophobic interior of membranes, and the presence of DHA among these fatty acids increases membrane permeability, fusion, and affects proteins residing in the membrane. Membrane proteins play various drug information roles in lymphocyte attack on cancer. On the cancer cell, proteins called class I major histocompatibility complex (MHC I) molecules alert lymphocytes that the cancer cell is abnormal, that is, bears tumor antigens. drug information On the lymphocyte, antigen receptors detect MHC I/tumor antigen drug information complexes and lead to lymphocyte activation; accessory membrane proteins help with the activation process, and a variety of other membrane proteins participate in the lymphocyte response that eventually leads to cancer cell destruction. What is happening at the cell membranes that produces DHA's beneficial effect in reducing growth of certain cancers? We believe that membranes are not homogeneous cell coats but rather are complex structures divided into many different patches called domains.
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