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| culinary institute for kids, coronary, benefit, hispanic advertising, raw milk, detox, freudian slip, media room, anabolics, coat, n 3, illustrated, lemagazine, low cholesteroldiet, eyes, rosacea, maggie snowling, burns, plump video , ldl c, medical, arteriosclerosis, | Maternal hospital days; Fatty acid constituents in maternal plasma samples, before and after supplementation; Postpartum hemorrhage; FETAL AND NEONATAL: Fetal and neonatal death; Gestational age at delivery; Small for gestational age; Birth weight; Apgar score at 1 and alpha僕ipoic acid 5 minutes; Number of alpha僕ipoic acid days of neonatal respiratory therapy; Admission to NICU and total number of days alpha僕ipoic acid in hospital; Intraventricular hemorrhage; Retinopathy of prematurity; Necrotizing enterocolitis; Deep infection; Periventricular leukomalacia; Bronchopulmonary dysplasia; Respiratory distress syndrome; Composite neonatal outcome Expected Total Enrollment: 800 Study start: February 2005; Expected completion: March 2008Data entry closure: December 2007 Preterm birth is the leading cause of perinatal mortality and morbidity. In a recently completed trial of weekly injections of 17 alpha hydroxyprogesterone caproate (17P), the National Institute of Child Health and Human Development (NICHD) Maternal Fetal Medicine Units (MFMU) Network found the treatments significantly beneficial in the prevention of recurrent preterm birth. |
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| The low cholesteroldiet trial will compare Omega-3 fatty acid with placebo in women receiving 17P therapy. The hypothesis being tested is: "Among women at high risk for preterm birth receiving weekly injections of 17P, the addition low cholesteroldiet of Omega-3 nutritional supplement will further reduce the rate of preterm birth." Condition Intervention Phase Preterm Birth Drug: 17 P Hydroxyprogesterone Caproate and Omega-3 fish oils Phase III MedlinePlus related topics: High Risk Pregnancy Study Type: InterventionalStudy Design: Prevention, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study Official Title: A Randomized Trial of Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in low cholesteroldiet Pregnancies at High Risk Further study details as provided by National Institute of Child Health and Human Development (NICHD): Primary Outcomes: Delivery less than 37 completed weeks gestation including any miscarriages occurring after randomizationSecondary Outcomes: MATERNAL: Delivery less than 35 weeks; Delivery less than 32 weeks; Spontaneous preterm delivery; Indicated preterm delivery; Tocolytic therapy; Time from randomization to delivery; Delivery on or after 41 weeks of gestation; Occurrence of gestational hypertension or preeclampsia; |
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