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| fat, caregiver of elderly, diabetes, 24 7 fat girls , probiotic, plump woman , askthe dietitian, vitamin e, carotenoid, politics in education, investor, hispanic newswire, children, flax seeds, transparency, lipid management, plump naked , colleges grad schools, trans fats, rheumatoid, | 17 Regulation of Gene Expression The results of cell culture and fatty oils animal studies indicate that omega-6 and omega-3 fatty acids can modulate the expression of a number fatty oils of genes, including those involved with fatty acid metabolism and inflammation.17, 18 Although the mechanisms require further clarification, omega-6 and omega-3 fatty acids may regulate gene expression by interacting with specific transcription factors, including peroxisome proliferator-activated receptors (PPARs) and liver X receptors (LXRs).19 Deficiency Essential Fatty fatty oils Acid Deficiency Clinical signs of essential fatty acid deficiency include a dry scaly rash, decreased growth in infants and children, increased susceptibility to infection and poor wound healing.20 Omega-3, omega-6 and omega-9 fatty acids compete for the same desaturase enzymes. |
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| Eicosanoid Synthesis Eicosanoids are potent chemical messengers caregiver of elderly derived from 20-carbon PUFA that play critical roles in immune and inflammatory responses. During an inflammatory response, DGLA, AA and EPA in cell membranes can be metabolized by enzymes known as cyclooxygenases and lipoxygenases to form prostaglandins and leukotrienes, respectively (Figure caregiver of elderly 2). In those who consume typical Western diets, the amount of AA in cell membranes is much greater than the amount of EPA, resulting in the formation of more eicosanoids derived from AA than EPA. However, increasing omega-3 fatty acid intake increases the EPA content of cell membranes, resulting in higher caregiver of elderly proportions of eicosanoids derived from EPA. Physiological responses to AA-derived eicosanoids differ from responses to EPA-derived eicosanoids. In general, eicosanoids derived from EPA are less potent inducers of inflammation, blood vessel constriction, and coagulation than eicosanoids derived from AA.3, |
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