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g of omega-3 fatty acids per month, equivalent monounsaturated to two fatty fish meals monounsaturated per week, was associated with a 50% reduced risk of primary cardiac arrest).22 In the US monounsaturated Physicians’ Health Study, men who consumed fish at least once weekly had a relative risk of sudden death of 0.48 (P=0.04) versus men who consumed fish less than once per month.12 A recent report from the Physicians’ Health Study23 reported an inverse relationship between blood levels of long-chain omega-3 fatty acids and risk of sudden death in men without a history of CVD. The relative risk of sudden death was significantly lower among men with levels in the third quartile (RR=0.28) and the fourth quartile (RR=0.19) compared with men whose blood levels were in the first quartile. Further evidence for a protective effect of omega-3 fatty acids comes from two recent studies by Landmark et al24,25 who reported that chronic intake of fish or fish oil was associated with a reduction in infarct size as estimated by the frequency of Q-wave infarcts and by peak creatine kinase and lactate dehydrogenase activities after MI.
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